Betrixaban maleate [Cas No. 936539-80-9]
Catalog No:TA-T4980
Manufacturer:TargetMol
CAS No.:936539-80-9
Formula:C27H26ClN5O7
MWt:567.98
€88,00 – €658,00
Name: | Betrixaban maleate |
Category: | Biochemicals |
Description: | Betrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa [1]. It was selected among all lead compounds due to its low hERG channel affinity while sustaining its factor Xa inhibition capacity [3]. Betrixaban, now developed by Portola Pharmaceuticals Inc., is prescribed as a venous thromboembolism (VTE) prophylactic for adult patients with moderate to severe restricted motility or with other risks for VTE [2]. VTE can be manifested as deep vein thrombosis or pulmonary embolism and it is a leading cause of preventable death in hospitalized patients [4]. |
Pathway: | Metabolism |
Target: | Factor Xa |
Receptor: | Factor Xa |
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