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Western blot analysis of extracts of various cell lines, using Exportin 2 (XPO2) antibody (A9510) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 5s.
Exportin 2 (XPO2) Rabbit pAb
Catalog No：AB-A9510
Manufacturer：ABclonal
Synonyms：CSE1L;CAS;CSE1;XPO2
Applications：WB,IHC
Reactivity：Human,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | Exportin 2 (XPO2) Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Exportin 2 (XPO2) (NP_001243064.1). |
| Gene ID: | 1434 |
| Swiss prot: | P55060 |
| Molecular weight: | 22kDa/103kDa/107kDa/110kDa |
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