Western blot analysis of extracts of various cell lines, using Exportin 2 (XPO2) Rabbit mAb (A1041) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
Exportin 2 (XPO2) Rabbit mAb
Catalog No:AB-A1041
Manufacturer:ABclonal
Synonyms:CAS, CSE1, XPO2
Applications:WB
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €485,00
Product Name: | Exportin 2 (XPO2) Rabbit mAb |
Category: | Monoclonal Antibodies |
Description: | Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012] |
Immunogen: | A synthesized peptide derived from human Exportin 2 (XPO2) |
Gene ID: | 1434 |
Swiss prot: | P55060 |
Molecular weight: | 98kDa |
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