Western blot analysis of extracts of various cell lines, using ERLIN2 antibody (A8314) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
ERLIN2 Rabbit pAb
Catalog No:AB-A8314
Manufacturer:ABclonal
Synonyms:ERLIN2;C8orf2;Erlin-2;NET32;SPFH2;SPG18;erlin-2
Applications:WB
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | ERLIN2 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a member of the SPFH domain-containing family of lipid raft-associated proteins. The encoded protein is localized to lipid rafts of the endoplasmic reticulum and plays a critical role in inositol 1,4,5-trisphosphate (IP3) signaling by mediating ER-associated degradation of activated IP3 receptors. Mutations in this gene are a cause of spastic paraplegia-18 (SPG18). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-152 of human ERLIN2 (NP_001003790.1). |
Gene ID: | 11160 |
Swiss prot: | O94905 |
Molecular weight: | 16kDa/22kDa/37kDa |
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