Western blot analysis of extracts of various cell lines, using ERBB2IP antibody (A8585) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
ERBB2IP Rabbit pAb
Catalog No:AB-A8585
Manufacturer:ABclonal
Synonyms:ERBIN;ERBB2IP;HEL-S-78;LAP2;erbin
Applications:WB
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | ERBB2IP Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1152-1371 of human ERBB2IP (NP_061165.1). |
Gene ID: | 55914 |
Swiss prot: | Q96RT1 |
Molecular weight: | 146-159kDa |
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