Dovitinib lactate hydrate [Cas No. 915769-50-5]
Catalog No:TA-T6479
Manufacturer:TargetMol
Synonyms:Dovitinib (TKI258) Lactate,TKI258
CAS No.:915769-50-5
Formula:C24H27FN6O4
MWt:482.51
€50,00 – €778,00
Name: | Dovitinib Lactate |
Category: | Biochemicals |
Description: | Dovitinib (TKI258) Lactate is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGFR1 and HER2. Phase 4. |
Pathway: | Angiogenesis, Tyrosine Kinase/Adaptors |
Target: | c-Kit inhibitor, FGFR inhibitor, FLT inhibitor, VEGFR inhibitor |
Receptor: | c-Kit, FGFR1, FGFR3, FLT3, VEGFR3/FLT4 |
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