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Immunohistochemistry of paraffin-embedded mouse pancreas using EDN3 Antibody (A13974) at dilution of 1:100 (40x lens).
EDN3 Rabbit pAb
Catalog No：AB-A13974
Manufacturer：ABclonal
Synonyms：EDN3;ET-3;ET3;HSCR4;PPET3;WS4B
Applications：IHC
Reactivity：Mouse
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | EDN3 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Altered expression of this gene is implicated in tumorigenesis. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 17-238 of human EDN3 (NP_996917.1). |
| Gene ID: | 1908 |
| Swiss prot: | P14138 |
| Molecular weight: | 23kDa/25kDa |
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