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Western blot analysis of extracts of various cell lines, using EBP antibody (A14845) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 5s.
EBP Rabbit pAb
Catalog No：AB-A14845
Manufacturer：ABclonal
Synonyms：EBP;CDPX2;CHO2;CPX;CPXD;MEND
Applications：WB
Reactivity：Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | EBP Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The protein encoded by this gene is an integral membrane protein of the endoplasmic reticulum. It is a high affinity binding protein for the antiischemic phenylalkylamine Ca2+ antagonist [3H]emopamil and the photoaffinity label [3H]azidopamil. It is similar to sigma receptors and may be a member of a superfamily of high affinity drug-binding proteins in the endoplasmic reticulum of different tissues. This protein shares structural features with bacterial and eukaryontic drug transporting proteins. It has four putative transmembrane segments and contains two conserved glutamate residues which may be involved in the transport of cationic amphiphilics. Another prominent feature of this protein is its high content of aromatic amino acid residues (>23%) in its transmembrane segments. These aromatic amino acid residues have been suggested to be involved in the drug transport by the P-glycoprotein. Mutations in this gene cause Chondrodysplasia punctata 2 (CDPX2; also known as Conradi-Hunermann syndrome). |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human EBP (NP_006570.1). |
| Gene ID: | 10682 |
| Swiss prot: | Q15125 |
| Molecular weight: | 26kDa |
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