Western blot analysis of extracts of various cell lines, using DMAP1 antibody (A19281) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 180s.
DMAP1 Rabbit mAb
Catalog No:AB-A19281
Manufacturer:ABclonal
Synonyms:DMAP1; DNMAP1; DNMTAP1; EAF2; MEAF2; SWC4; DNA methyltransferase 1-associated protein 1
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €485,00
Product Name: | DMAP1 Rabbit mAb |
Category: | Monoclonal Antibodies |
Description: | This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described. |
Immunogen: | Recombinant protein of human DMAP1. |
Gene ID: | 55929 |
Swiss prot: | Q9NPF5 |
Molecular weight: | 53kDa |
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