Dacomitinib hydrate [Cas No. 1042385-75-0]
Catalog No：TA-T19965
Manufacturer：TargetMol
Synonyms：PF-00299804,PF00299804,PF 00299804,PF299804,PF-299804,PF 299804
CAS No.：1042385-75-0
Formula：C24H27ClFN5O3
MWt：487.96
€61,00 – €1.530,00
| Name: | Dacomitinib hydrate |
| Category: | Biochemicals |
| Description: | Dacomitinib hydrate is a highly selective and second-generation small-molecule inhibitor of the pan-epidermal growth factor receptor family of tyrosine kinases. Dacomitinib specifically and irreversibly binds to and inhibits human EGFR subtypes, resulting in inhibition of proliferation and induction of apoptosis in EGFR-expressing tumor cells. |
| Pathway: | Angiogenesis,JAK/STAT signaling,Tyrosine Kinase/Adaptors |
| Target: | EGFR |
| Receptor: | EGFR |
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