(R)-(-)-Gossypol acetic acid [Cas No. 866541-93-7]
Catalog No:TA-T6396
Manufacturer:TargetMol
Synonyms:(-)-Gossypol acetic acid,(R)-Gossypol acetic acid,(R)-(-)-Gossypol acetic acid,AT-101 (acetic acid),AT101
CAS No.:866541-93-7
Formula:C30H30O8﹞C2H4O2
MWt:578.61
€63,00 – €1.280,00
Name: | AT101 acetate |
Category: | Biochemicals |
Description: | AT101, the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32 μM, 0.48 μM and 0.18 μM, does not inhibit BIR3 domain and BID. Phase 2. |
Pathway: | Apoptosis |
Target: | BCL inhibitor |
Receptor: | Mcl-1, Bcl-2, Bcl-xL |
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