HS 014 acetate(207678-81-7 free base)
Catalog No:TA-TP2015L
Manufacturer:TargetMol
CAS No.:TP2015L
Formula:C73H98N20O19S2
MWt:1623.83
€342,00 – €4.680,00
Name: | HS 014 acetate(207678-81-7 free base) |
Category: | Biochemicals |
Description: | HS 014 acetate is a potent and selective melanocortin MC4 receptor antagonist (Ki values are 3.16, 108, 54.4 and 694 nM for cloned human MC4, MC1, MC3 and MC5 receptors respectively). Increases food intake in rats and nociception in mice following central administration in vivo. Also inhibits IL-1β-induced Fos expression in the paraventricular hypothalamus. |
Pathway: | GPCR/G Protein,Neuroscience |
Target: | Melanocortin Receptor |
Receptor: | melanocortin-4 receptor (MC4R) |
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