Defensin HNP- 3 (human)
Catalog No:CP-DEFS-007C
Manufacturer:CPC Scientific
Size:1 mg
CAS No.:136661-76-2
Formula:C151H222 N44O40S 6
MWt:3,486
€1.211,00
Product Name: | Defensin HNP- 3 (human) |
Category: | Peptides |
Three letter sequence: | Asp-Cys-Tyr- Cys-Arg-Ile- Pro-Ala-Cys- Ile-Ala-Gly- Glu-Arg-Arg- Tyr-Gly-Thr- Cys-Ile-Tyr- Gln-Gly-Arg- Leu-Trp-Ala- Phe-Cys- Cys(Cys2 and Cys30/Cys4 and Cys19/Cys9 and Cys29 Bridge) |
One letter sequence: | DCYCRIPACIA GERRYGTCIYQ GRLWAFCC(Cy s2 and Cys30/Cys4 and Cys19/Cys9 and Cys29 Bridge) |
Description: | This peptide contain 6 conserved disulfide-linked cysteines. In vitro, it has a prominent antimicrobial activities against bacteria, fungi, and certain enveloped viruses. In addition, human and rabbit defensins exert potent cytotoxicity in vitro against various mammalian tumor cells. |
Literature References: | P.A.Raj et al., Biochem. J., 347, 633 (2000) F.T.Lundy et al., Oral Oncol., 40, 139 (2004) Z.Wu et al., J. Pept. Res., 64, 118 (2004) |
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