Western blot analysis of extracts of various cell lines, using DCTN1 antibody (A1783) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
DCTN1 Rabbit pAb
Catalog No:AB-A1783
Manufacturer:ABclonal
Synonyms:DCTN1;DAP-150;DP-150;P135
Applications:WB,IF,IP
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | DCTN1 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes the largest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. Dynactin is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. Mutations in this gene cause distal hereditary motor neuronopathy type VIIB (HMN7B) which is also known as distal spinal and bulbar muscular atrophy (dSBMA). |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 945-1139 of human DCTN1 (NP_001128513.1). |
Gene ID: | 1639 |
Swiss prot: | Q14203 |
Molecular weight: | 126kDa/127kDa/136kDa/138kDa/140kDa/141kDa |
Help & Support
Product
Guarantee and
Expert Support
Related products
Catalog No:AB-A0068
Manufacturer:ABclonal
Synonyms:BCR;ALL;BCR1;CML;D22S11;D22S662;PHL
Applications:WB,IHC
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Catalog No:AB-A0040
Manufacturer:ABclonal
Synonyms:MET;AUTS9;DFNB97;HGFR;RCCP2;c-Met
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Catalog No:AB-A0053
Manufacturer:ABclonal
Synonyms:TXN;TRDX;TRX;TRX1
Applications:WB,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Catalog No:AB-A0019
Manufacturer:ABclonal
Synonyms:CASP9;APAF-3;APAF3;ICE-LAP6;MCH6;PPP1R56;caspase-9;casp9;Caspase 9
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Catalog No:AB-A0010
Manufacturer:ABclonal
Synonyms:ADPRT;ADPRT 1;ADPRT1;ARTD1;PARP;PARP-1;PPOL;pADPRT-1;PARP1;Cleaved PARP;PARP1
Applications:WB,IHC,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €605,00
Catalog No:AB-A0013
Manufacturer:ABclonal
Synonyms:CK-4, CK4, CYK4, K4, WSN1
Applications:WB,IHC,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €485,00