AMG 487 [Cas No. 473719-41-4]
Catalog No：TA-T10297L
Manufacturer：TargetMol
CAS No.：473719-41-4
Formula：C32H28F3N5O4
MWt：603.59
€48,00 – €1.618,00
| Name: | AMG 487 |
| Category: | Biochemicals |
| Description: | AMG 487 prevents the chemokines I-IP-10 and I-ITAC from binding to CXCR3. In the cellular assays, AMG 487 inhibits CXCR3-mediated cell migration with IC50 values of 8nM, 15nM and 36nM for I-IP-10, I-ITAC and MIG, respectively. |
| Pathway: | Autophagy, GPCR/G Protein, Immunology & Inflammation |
| Target: | CXCR |
| Receptor: | CXCR3 |
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