Western blot analysis of extracts of various cell lines, using CTSK antibody (A5871) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Enhanced Kit (RM00021).|Exposure time: 3s.
CTSK Rabbit pAb
Catalog No:AB-A5871
Manufacturer:ABclonal
Synonyms:CTSK;CTS02;CTSO;CTSO1;CTSO2;PKND;PYCD
Applications:WB,IHC
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €295,00
Product Name: | CTSK Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 115-329 of human CTSK (NP_000387.1). |
Gene ID: | 1513 |
Swiss prot: | P43235 |
Molecular weight: | 36kDa |
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