Linsitinib [Cas No. 867160-71-2]
Catalog No：TA-T6017
Manufacturer：TargetMol
Synonyms：OSI-906
CAS No.：867160-71-2
Formula：C26H23N5O
MWt：421.49
€29,00 – €249,00
| Name: | Linsitinib |
| Category: | Biochemicals |
| Description: | OSI-906 (Linsitinib) is an orally bioavailable small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with potential antineoplastic activity. Linsitinib selectively inhibits IGF-1R, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. Overexpressed in a variety of human cancers, IGF-1R stimulates cell proliferation, enables oncogenic transformation, and suppresses apoptosis. |
| Pathway: | Others, Tyrosine Kinase/Adaptors |
| Target: | IGF-1R inhibitor, Others inhibitor |
| Receptor: | IGF-1R, Insulin Receptor, IRR |
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