KY19382 [Cas No. 2226664-93-1]
Catalog No：TA-T9025
Manufacturer：TargetMol
Synonyms：2H-Indol-2-one, 5,6-dichloro-3-[1,3-dihydro-3-(methoxyimino)-2H-indol-2-ylidene]-1,3-dihydro-Ky19382,A3051
CAS No.：2226664-93-1
Formula：C17H11Cl2N3O2
MWt：360.2
€149,00 – €2.430,00
| Name: | KY19382 |
| Category: | Biochemicals |
| Description: | KY19382 is a potent and orally active dual inhibitor of CXXC5-DVL and GSK3β( IC50s of 19 and 10 nM, respectively). It activates Wnt/β-catenin signaling through inhibitory effects on both CXXC5-DVL interaction and GSK3β activity. KY19382 can be used for the research of high fat diet (HFD) induced metabolic diseases. |
| Pathway: | PI3K/Akt/mTOR signaling,Stem Cells |
| Target: | GSK-3 |
| Receptor: | CXXC5-DVL,GSK-3β |
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