Propantheline bromide [Cas No. 50-34-0]
Catalog No：TA-T1006
Manufacturer：TargetMol
Synonyms：Pro-Banthine,Neometantyl,Neopepulsan
CAS No.：50-34-0
Formula：C23H30BrNO3
MWt：448.4
€38,00 – €82,00
| Name: | Propantheline bromide |
| Category: | Biochemicals |
| Description: | Propantheline bromide competitively antagonizes acetylcholine activity mediated by muscarinic receptors at neuroeffector sites on smooth muscle and exocrine gland cells. Propantheline Bromide is the bromide salt form of propantheline, a quaternary ammonium compound structurally related to belladonna alkaloids. An aspartic acid residue present in the N-terminal portion of the third transmembrane helix of the muscarinic receptor is believed to form an ionic bond with the tertiary or quaternary nitrogen of the antagonist. Antagonism leads to a reduction of exocrine glands secretions and to relax the bronchial muscle and reduce tone and motility of intestinal smooth muscle. |
| Pathway: | Neuroscience |
| Target: | AChR antagonist |
| Receptor: | mAChR |
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