CHIR-124 [Cas No. 405168-58-3]
Catalog No:TA-T6350
Manufacturer:TargetMol
Synonyms:CHIR 124,CHIR-124
CAS No.:405168-58-3
Formula:C23H22ClN5O
MWt:419.91
€55,00 – €538,00
Name: | CHIR124 |
Category: | Biochemicals |
Description: | CHIR-124 is an effective Chk1 inhibitor (IC50: 0.3 nM). It has 2, 000-fold selectivity against Chk2, 500- to 5, 000-fold less activity against Cdc2 and CDK2/4. |
Pathway: | PI3K/Akt/mTOR signaling, Angiogenesis, Cell Cycle/Checkpoint, Stem Cells, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic |
Target: | Chk inhibitor, FLT inhibitor, GSK-3 inhibitor, PDGFR inhibitor, Src inhibitor |
Receptor: | Chk1, FLT3, GSK-3, PDGFR, Fyn |
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