Western blot analysis of extracts of various cell lines, using CLDN19 Antibody (A2874) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 40s.
CLDN19 Rabbit pAb
Catalog No:AB-A2874
Manufacturer:ABclonal
Synonyms:CLDN19;HOMG5
Applications:WB
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | CLDN19 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-80 of human CLDN19 (NP_001116867.1). |
Gene ID: | 149461 |
Swiss prot: | Q8N6F1 |
Molecular weight: | 22kDa/23kDa |
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