Semagacestat [Cas No. 425386-60-3]
Catalog No:TA-T6125
Manufacturer:TargetMol
Synonyms:LY450139
CAS No.:425386-60-3
Formula:C19H27N3O4
MWt:361.44
€44,00 – €678,00
Name: | Semagacestat |
Category: | Biochemicals |
Description: | Semagacestat (LY450139) is a γ-secretase blocker for Aβ42/Aβ40/Aβ38 (IC50: 10.9/12.1/12.0 nM) and also inhibits Notch signaling (IC50: 14.1 nM). |
Pathway: | Neuroscience, Proteases & Proteasome, Stem Cells |
Target: | Gamma-secretase inhibitor |
Receptor: | Notch, γ secretase(Aβ38), γ secretase(Aβ40), γ secretase(Aβ42) |
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