Semagacestat [Cas No. 425386-60-3]
Catalog No：TA-T6125
Manufacturer：TargetMol
Synonyms：LY450139
CAS No.：425386-60-3
Formula：C19H27N3O4
MWt：361.44
€44,00 – €678,00
| Name: | Semagacestat |
| Category: | Biochemicals |
| Description: | Semagacestat (LY450139) is a γ-secretase blocker for Aβ42/Aβ40/Aβ38 (IC50: 10.9/12.1/12.0 nM) and also inhibits Notch signaling (IC50: 14.1 nM). |
| Pathway: | Neuroscience, Proteases & Proteasome, Stem Cells |
| Target: | Gamma-secretase inhibitor |
| Receptor: | Notch, γ secretase(Aβ38), γ secretase(Aβ40), γ secretase(Aβ42) |
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