[Cit26]-Histone H3 (21-44)- GGK(Biotin)
Catalog No：CP-HIST-057B
Manufacturer：CPC Scientific
Size：1 mg
CAS No.：N/A
MWt：2,976
€356,00
| Product Name: | [Cit26]-Histone H3 (21-44)- GGK(Biotin) |
| Category: | Peptides |
| Three letter sequence: | Ala-Thr-Lys- Ala-Ala-Cit- Lys-Ser-Ala- Pro-Ala-Thr- Gly-Gly-Val- Lys-Lys-Pro- His-Arg-Tyr- Arg-Pro-Gly- Gly-Gly- Lys(Biotin) |
| One letter sequence: | ATKAA-Cit- KSAPATGGVK KPHRYRPGGG- K(Biotin) |
| Description: | This peptide is the fragment of Histone H3 (21-44) with deimination at Arg26, converting it to Cit (citrulline). It is biotinylated through a C-terminal GGK linker. Deimination by peptidyl arginine deiminase 4 (PADI4) blocks methylation by the CARM1 methyltransferase and inhibits transcriptional activation. |
| Literature References: | Cuthbert, G. et al. Cell 118, 545 (2004). |
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