Western blot analysis of extracts of NIH/3T3, using CIC antibody (A15408) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
CIC Rabbit pAb
Catalog No:AB-A15408
Manufacturer:ABclonal
Synonyms:CIC
Applications:WB
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | CIC Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The protein encoded by this gene is an ortholog of the Drosophila melanogaster capicua gene, and is a member of the high mobility group (HMG)-box superfamily of transcriptional repressors. This protein contains a conserved HMG domain that is involved in DNA binding and nuclear localization, and a conserved C-terminus. Studies suggest that the N-terminal region of this protein interacts with Atxn1 (GeneID:6310), to form a transcription repressor complex, and in vitro studies suggest that polyglutamine-expansion of ATXN1 may alter the repressor activity of this complex. Mutations in this gene have been associated with olidogdendrogliomas (PMID:21817013). In addition, translocation events resulting in gene fusions of this gene with both DUX4 (GeneID:100288687) and FOXO4 (GeneID:4303) have been associated with round cell sarcomas. There are multiple pseudogenes of this gene found on chromosomes 1, 4, 6, 7, 16, 20, and the Y chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1379-1608 of human CIC (NP_055940.3). |
Gene ID: | 23152 |
Swiss prot: | Q96RK0 |
Molecular weight: | 163kDa |
Help & Support
Product
Guarantee and
Expert Support
Related products
Catalog No:AB-A0137
Manufacturer:ABclonal
Synonyms:TERF1;PIN2;TRBF1;TRF;TRF1;hTRF1-AS;t-TRF1
Applications:WB,IHC
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Catalog No:AB-A0094
Manufacturer:ABclonal
Synonyms:CDKN2, p33(CDK2)
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €485,00
Catalog No:AB-A0064
Manufacturer:ABclonal
Synonyms:MSH2;COCA1;FCC1;HNPCC;HNPCC1;LCFS2
Applications:WB,IF
Reactivity:Human
Host:Rabbit
Conjugate:No
€245,00 – €370,00
Catalog No:AB-A0054
Manufacturer:ABclonal
Synonyms:AGM7;GRB1;IMD36;p85;p85-ALPHA;PI3 Kinase p85 alpha;PIK3R1
Applications:WB,IHC
Reactivity:Human,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Catalog No:AB-A0052
Manufacturer:ABclonal
Synonyms:MGMT
Applications:WB
Reactivity:Human,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Catalog No:AB-A0033
Manufacturer:ABclonal
Synonyms:TNFRSF1A;CD120a;FPF;TBP1;TNF-R;TNF-R-I;TNF-R55;TNFAR;TNFR1;TNFR55;TNFR60;p55;p55-R;p60
Applications:IF
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €370,00