Western blot analysis of extracts of various cell lines, using CHMP2B antibody (A19244) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
CHMP2B Rabbit mAb
Catalog No:AB-A19244
Manufacturer:ABclonal
Synonyms:CHMP2B; ALS17; CHMP2.5; DMT1; VPS2-2; VPS2B; charged multivesicular body protein 2b
Applications:WB,IHC
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €485,00
Product Name: | CHMP2B Rabbit mAb |
Category: | Monoclonal Antibodies |
Description: | This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration. |
Immunogen: | Recombinant protein of human CHMP2B. |
Gene ID: | 25978 |
Swiss prot: | Q9UQN3 |
Molecular weight: | 28kDa |
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