Western blot analysis of extracts of various cell lines, using CFP antibody (A16414) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
CFP Rabbit pAb
Catalog No:AB-A16414
Manufacturer:ABclonal
Synonyms:CFP;BFD;PFC;PFD;PROPERDIN;properdin
Applications:WB
Reactivity:Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | CFP Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 190-469 of human CFP (NP_001138724.1). |
Gene ID: | 5199 |
Swiss prot: | P27918 |
Molecular weight: | 51kDa |
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