Western blot analysis of extracts of various cell lines, using CFH antibody (A13686) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
CFH Rabbit pAb
Catalog No:AB-A13686
Manufacturer:ABclonal
Synonyms:CFH;AHUS1;AMBP1;ARMD4;ARMS1;CFHL3;FH;FHL1;HF;HF1;HF2;HUS
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | CFH Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 270-445 of human CFH (NP_001014975.1). |
Gene ID: | 3075 |
Swiss prot: | P08603 |
Molecular weight: | 51kDa/139kDa |
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