Western blot analysis of extracts of various cell lines, using CFD antibody (A8117) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 20s.
CFD Rabbit pAb
Catalog No:AB-A8117
Manufacturer:ABclonal
Synonyms:CFD;ADIPSIN;ADN;DF;PFD
Applications:WB,IHC
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | CFD Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-253 of human CFD (NP_001919.2). |
Gene ID: | 1675 |
Swiss prot: | P00746 |
Molecular weight: | 27kDa |
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