.jpg)
Western blot analysis of extracts of 293T cells, using CDKN1A/p21CIP1 antibody (A1483) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
.jpg)
Western blot analysis of extracts of various cell lines, using CDKN1A/p21CIP1 antibody (A1483) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
CDKN1A/p21CIP1 Rabbit pAb
Catalog No：AB-A1483
Manufacturer：ABclonal
Synonyms：CAP20;CDKN1;CIP1;MDA-6;P21;SDI1;WAF1;p21CIP1;CDKN1A
Applications：WB,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | CDKN1A/p21CIP1 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-cyclin-dependent kinase2 or -cyclin-dependent kinase4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen, a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of cyclin-dependent kinase2, and may be instrumental in the execution of apoptosis following caspase activation. Mice that lack this gene have the ability to regenerate damaged or missing tissue. Multiple alternatively spliced variants have been found for this gene. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 43-142 of human CDKN1A/p21CIP1 (NP_000380.1). |
| Gene ID: | 1026 |
| Swiss prot: | P38936 |
| Molecular weight: | 21kDa |
Help & Support
Product
Guarantee and
Expert Support
Related products
Catalog No：AB-A0079
Manufacturer：ABclonal
Synonyms：FGF1;AFGF;ECGF;ECGF-beta;ECGFA;ECGFB;FGF-1;FGF-alpha;FGFA;GLIO703;HBGF-1;HBGF1
Applications：WB
Reactivity：Mouse
Host：Rabbit
Conjugate：No
€65,00 – €325,00
Catalog No：AB-A0067
Manufacturer：ABclonal
Synonyms：MMP-14, MMP-X1, MT-MMP, MT-MMP 1, MT1-MMP, MT1MMP, MTMMP1, WNCHRS
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €485,00
Catalog No：AB-A0068
Manufacturer：ABclonal
Synonyms：BCR;ALL;BCR1;CML;D22S11;D22S662;PHL
Applications：WB,IHC
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
Catalog No：AB-A0076
Manufacturer：ABclonal
Synonyms：BDPLT16;BDPLT2;CD61;GP3A;GPIIIa;GT;Integrin beta 3;ITGB3
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
Catalog No：AB-A0062
Manufacturer：ABclonal
Synonyms：CYP1A2;CP12;P3-450;P450(PA);CYPIA2
Applications：WB
Reactivity：Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
Catalog No：AB-A0038
Manufacturer：ABclonal
Synonyms：BRAF;B-RAF1;B-raf;BRAF1;NS7;RAFB1
Applications：WB,IHC
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00