Western blot analysis of extracts of various cell lines, using CDH3 antibody (A14235) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
CDH3 Rabbit pAb
Catalog No:AB-A14235
Manufacturer:ABclonal
Synonyms:CDH3;CDHP;HJMD;PCAD
Applications:WB,IHC,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | CDH3 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS). |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-350 of human CDH3 (NP_001784.2). |
Gene ID: | 1001 |
Swiss prot: | P22223 |
Molecular weight: | 86kDa/91kDa |
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