CD40 Rabbit mAb
Catalog No:AB-A20214
Manufacturer:ABclonal
Synonyms:CD40;Bp50;CDW40;TNFRSF5;p50
Applications:WB,ELISA,FC,IF
Reactivity:Human
Host:Rabbit
Conjugate:No
€245,00 – €370,00
Product Name: | CD40 Rabbit mAb |
Category: | Monoclonal Antibodies |
Description: | This gene is a member of the TNF-receptor superfamily. The encoded protein is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3). Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
Immunogen: | Recombinant protein of human CD40 |
Gene ID: | 958 |
Swiss prot: | P25942 |
Molecular weight: | 22kDa/30kDa |
Help & Support
Product
Guarantee and
Expert Support
Related products
Catalog No:AB-A0180
Manufacturer:ABclonal
Synonyms:ARAF;A-RAF;ARAF1;PKS2;RAFA1
Applications:WB,IF
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Catalog No:AB-A0185
Manufacturer:ABclonal
Synonyms:GDF15;GDF-15;MIC-1;MIC1;NAG-1;PDF;PLAB;PTGFB
Applications:WB,IHC,IF,IP
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Catalog No:AB-A0169
Manufacturer:ABclonal
Synonyms:CASP10;ALPS2;FLICE2;MCH4;caspase-10
Applications:IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Catalog No:AB-A0066
Manufacturer:ABclonal
Synonyms:KAT2B;CAF;P/CAF;PCAF
Applications:WB,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Catalog No:AB-A0024
Manufacturer:ABclonal
Synonyms:FADK;FAK;FAK1;FRNK;PPP1R71;p125FAK;pp125FAK;PTK2
Applications:WB,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €295,00
Catalog No:AB-A0027
Manufacturer:ABclonal
Synonyms:CANDF7;IMD31A;IMD31B;IMD31C;ISGF-3;STAT91;STAT1 alpha;STAT1
Applications:WB,IHC
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00