CD3E+CD3G Rabbit mAb
Catalog No:AB-A20213
Manufacturer:ABclonal
Synonyms:CD3E;IMD18;T3E;TCRE;CD3e molecule;CD3G;CD3-GAMMA;IMD17;T3G
Applications:WB,ELISA,FC,IF
Reactivity:Human
Host:Rabbit
Conjugate:No
€245,00 – €370,00
Product Name: | CD3E+CD3G Rabbit mAb |
Category: | Monoclonal Antibodies |
Description: | The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency. |
Immunogen: | Recombinant protein of human CD3E+CD3G . |
Gene ID: | 916/917 |
Swiss prot: | P07766/P09693 |
Molecular weight: | 23kDa |
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