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Western blot analysis of extracts of various cell lines, using CD172a/SIRPα antibody (A9001) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
CD172a/SIRPα Rabbit pAb
Catalog No：AB-A9001
Manufacturer：ABclonal
Synonyms：SIRPA;BIT;CD172A;MFR;MYD-1;P84;PTPNS1;SHPS1;SIRP
Applications：WB,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | CD172a/SIRP伪 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 395-504 of human CD172a/SIRP伪 (NP_542970.1). |
| Gene ID: | 140885 |
| Swiss prot: | P78324 |
| Molecular weight: | 54kDa/55kDa |
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