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Western blot analysis of extracts of various cell lines, using CD11b/ITGAM antibody (A1581) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.
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Immunohistochemistry of paraffin-embedded human tonsil using CD11b/ITGAM antibody (A1581) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse spleen using CD11b/ITGAM antibody (A1581) at dilution of 1:100 (40x lens).
CD11b/ITGAM Rabbit pAb
Catalog No：AB-A1581
Manufacturer：ABclonal
Synonyms：CD11B;CR3A;MAC-1;MAC1A;MO1A;SLEB6;ITGAM;CD11b/ITAM
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | CD11b/ITGAM Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 (‘Mac-1’), or inactivated-C3b (iC3b) receptor 3 (‘CR3’). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-330 of human CD11b/ITGAM (NP_001139280.1). |
| Gene ID: | 3684 |
| Swiss prot: | P11215 |
| Molecular weight: | 127kDa |
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