Western blot analysis of extracts of Mouse lung, using CCR1 Rabbit pAb (A18341) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
CCR1 Rabbit pAb
Catalog No:AB-A18341
Manufacturer:ABclonal
Synonyms:CD191;CKR-1;CKR1;CMKBR1;HM145;MIP1aR;SCYAR1;CCR1
Applications:WB,IHC,IF
Reactivity:Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | CCR1 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008] |
Immunogen: | A synthetic peptide of human CCR1. |
Gene ID: | 1230 |
Swiss prot: | P32246 |
Molecular weight: |
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