Western blot analysis of extracts of various cell lines, using CCDC88A antibody (A16132) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
CCDC88A Rabbit pAb
Catalog No:AB-A16132
Manufacturer:ABclonal
Synonyms:CCDC88A;APE;GIRDIN;GIV;GRDN;HkRP1;KIAA1212;PEHO;girdin
Applications:WB
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | CCDC88A Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1571-1870 of human CCDC88A (NP_001129069.1). |
Gene ID: | 55704 |
Swiss prot: | Q3V6T2 |
Molecular weight: | 207kDa/212kDa/215kDa/216kDa |
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