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Western blot analysis of extracts of U-87MG cells, using Caspr11 Rabbit mAb (A3721) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 3s.
Caspr1 Rabbit mAb
Catalog No：AB-A3721
Manufacturer：ABclonal
Synonyms：CASPR, CNTNAP, NRXN4, P190
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €485,00
| Product Name: | Caspr1 Rabbit mAb |
| Category: | Monoclonal Antibodies |
| Description: | The gene product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein,' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons. [provided by RefSeq, Jan 2009] |
| Immunogen: | A synthesized peptide derived from human Caspr11 |
| Gene ID: | 8506 |
| Swiss prot: | P78357 |
| Molecular weight: | 165kDa |
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