Western blot analysis of extracts of various cell lines, using CASP2 Polyclonal Antibody (A5724) at 1:1000 dilution.Jurkat cells were treated by Staurosporine(1uM) at room temperature for 3 hours .|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 3min.
Caspase-2 Rabbit pAb
Catalog No:AB-A5724
Manufacturer:ABclonal
Synonyms:CASP2;CASP-2;ICH1;NEDD-2;NEDD2;PPP1R57;caspase-2
Applications:WB,IHC
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | Caspase-2 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer’s disease, Huntington’s disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 153-452 of human Caspase-2 (NP_116764.2). |
Gene ID: | 835 |
Swiss prot: | P42575 |
Molecular weight: | 10kDa/34kDa/50kDa |
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