Caspase-11 Rabbit pAb
Catalog No：AB-A6495
Manufacturer：ABclonal
Synonyms：Cas; ich-; Caspa; Caspl; ich-3; CASP-4; Casp11; CASP-11
Applications：WB
Reactivity：Mouse
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | Caspase-11 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a member of the cysteine proteases that plays important roles in apoptosis, cell migration and the inflammatory response. The encoded protein mediates production of pro-inflammatory cytokines by macrophages upon bacterial infection. Mice lacking the encoded protein are resistant to endotoxic shock induced by lipopolysaccharide. A 5-bp deletion encompassing a splice acceptor junction resulting in alternate splicing and a shorter non-functional isoform in certain mouse strains has been described. Although its official nomenclature is “caspase 4, apoptosis-related cysteine peptidase”, this gene and its encoded protein have historically been called caspase 11. This gene is present in a cluster of three caspase genes on chromosome 9. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 81-266 of mouse Caspase-4 (P70343). |
| Gene ID: | 12363 |
| Swiss prot: | |
| Molecular weight: | 13kDa/18kDa/30kDa/36kDa/43kDa |
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