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Immunofluorescence analysis of HeLa cells using Caspase-10 Polyclonal Antibody (A0169) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Caspase-10 Rabbit pAb
Catalog No：AB-A0169
Manufacturer：ABclonal
Synonyms：CASP10;ALPS2;FLICE2;MCH4;caspase-10
Applications：IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | Caspase-10 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 230-505 of human Caspase-10 (NP_116759.2). |
| Gene ID: | 843 |
| Swiss prot: | Q92851 |
| Molecular weight: | 28kDa/31kDa/51kDa/54kDa/58kDa |
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