CARD8 Rabbit pAb
Catalog No:AB-A0293
Manufacturer:ABclonal
Synonyms:CARD8;CARDINAL;DACAR;DAKAR;NDPP;NDPP1;TUCAN
Applications:WB
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | CARD8 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human CARD8 (NP_003796.1). |
Gene ID: | 22900 |
Swiss prot: | Q9Y2G2 |
Molecular weight: | 32kDa/44kDa/48kDa/55kDa/60kDa |
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