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Western blot analysis of extracts of various cell lines, using CARD11 Rabbit mAb (A9652) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
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Immunohistochemistry of paraffin-embedded rat spleen using CARD11 Rabbit mAb (A9652) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse spleen using CARD11 Rabbit mAb (A9652) at dilution of 1:100 (40x lens).
CARD11 Rabbit mAb
Catalog No：AB-A9652
Manufacturer：ABclonal
Synonyms：BENTA, BIMP3, CARMA1, IMD11, PPBL
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €485,00
| Product Name: | CARD11 Rabbit mAb |
| Category: | Monoclonal Antibodies |
| Description: | The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008] |
| Immunogen: | A synthesized peptide derived from human CARD11 |
| Gene ID: | 84433 |
| Swiss prot: | Q9BXL7 |
| Molecular weight: | 133kDa |
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