Alvimopan [Cas No. 156053-89-3]
Catalog No：TA-T1242
Manufacturer：TargetMol
Synonyms：LY 246736,ADL 8-2698
CAS No.：156053-89-3
Formula：C25H32N2O4
MWt：424.53
€45,00 – €1.280,00
| Name: | Alvimopan |
| Category: | Biochemicals |
| Description: | Alvimopan is a synthetic trans-3, 4-dimethyl-4-(3-hydroxyphenyl) piperidine with peripherally selective opioid mu receptor antagonist activity. Alvimopan is a selective and competitive antagonist at mu-opioid receptors, found in myenteric and submucosal neurons and the immune cells of the lamina propria in the human gut. Upon administration, this agent binds to mu-opioid receptors in the gut, thereby reversing opioid-related disturbances in gut motility. Alvimopan is approximately three to nine times more potent than naloxone. |
| Pathway: | Endocrinology/Hormones, GPCR/G Protein, Neuroscience |
| Target: | Opioid Receptor antagonist |
| Receptor: | μ-opioid receptor |
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