AES-350 [Cas No. 847249-57-4]
Catalog No：TA-T9041
Manufacturer：TargetMol
CAS No.：847249-57-4
Formula：C18H20N2O3
MWt：312.36
€176,00 – €3.869,00
| Name: | AES-350 |
| Category: | Biochemicals |
| Description: | AES-350 is a potent and orally active HDAC6 inhibitor(IC50 and a Ki of 0.0244 μM and 0.035 μM, respectively). It is also against HDAC-3, -8, and -11 in an enzymatic activity assay with IC50 values of 0.187 μM, 0.245 μM, and >1μM, respectively. AES-350 triggers apoptosis in AML cells through HDAC inhibition and can be used for acute myeloid leukemia (AML) research. |
| Pathway: | Chromatin/Epigenetic,DNA Damage/DNA Repair |
| Target: | HDAC |
| Receptor: | HDAC11,HDAC3,HDAC6 |
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