Resiquimod [Cas No. 144875-48-9]
Catalog No:TA-T6964
Manufacturer:TargetMol
Synonyms:S28463,R848
CAS No.:144875-48-9
Formula:C17H22N4O2
MWt:314.38
€40,00 – €488,00
Name: | Resiquimod |
Category: | Biochemicals |
Description: | Resiquimod is an imidazoquinoline amine and Toll-like receptor (TLR) agonist with potential immune response modifying activity. Resiquimod exerts its effect through the TLR signaling pathway by binding to and activating TLR7 and 8 mainly on dendritic cells, macrophages, and B-lymphocytes. This induces the nuclear translocation of the transcription activator NF-kB as well as activation of other transcription factors. This may lead to an increase in mRNA levels and subsequent production of cytokines, especially interferon-alpha (INF-a) and other cytokines, thereby enhancing T-helper 1 (Th1) immune responses. In addition, topical application of resiquimod appears to activate Langerhans’ cells, leading to an enhanced activation of T-lymphocytes. |
Pathway: | Immunology & Inflammation |
Target: | TLR agonist |
Receptor: | TLR7, TLR8 |
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