Naratriptan hydrochloride [Cas No. 143388-64-1]
Catalog No:TA-T6602
Manufacturer:TargetMol
Synonyms:GR-85548A hydrochloride,Naratriptan HCl,Amerge,Naramig
CAS No.:143388-64-1
Formula:C17H25N3O2S﹞HCl
MWt:371.93
€48,00 – €491,00
Name: | Naratriptan hydrochloride |
Category: | Biochemicals |
Description: | Naratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-migraine property. Naratriptan hydrochloride binds selectively and with high affinity to the 5-HT1D and 5-HT1B receptor subtypes. Activation of these 5-HT1D/B receptors located on intracranial blood vessels leads to vasoconstriction and provides relief of migraine headaches. Naratriptan hydrochloride may also exerts its effect by stimulation of 5-HT1D/1B receptors on sensory nerve endings in the trigeminal system thereby decreasing the release of pro-inflammatory neuropeptides. |
Pathway: | GPCR/G Protein, Neuroscience |
Target: | 5-HT Receptor agonist |
Receptor: | 5-HT1 |
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