Western blot analysis of extracts of various cell lines, using C4BPB antibody (A6362) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
C4BPB Rabbit pAb
Catalog No:AB-A6362
Manufacturer:ABclonal
Synonyms:C4BPB;C4BP
Applications:WB,IHC,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | C4BPB Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 18-251 of human C4BPB (NP_001017364.1). |
Gene ID: | 725 |
Swiss prot: | P20851 |
Molecular weight: | 28kDa |
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