N-Acetyl-L-arginine [Cas No. 155-84-0]
Catalog No：TA-T8053
Manufacturer：TargetMol
CAS No.：155-84-0
Formula：C8H16N4O3
MWt：216.24
€55,00 – €58,00
| Name: | Ac-Arg-OH |
| Category: | Biochemicals |
| Description: | N-a-Acetyl-L-arginine, also known as N-ac-L-arg-OH or N-alpha-acetylarginine, belongs to the class of organic compounds known as n-acyl-l-alpha-amino acids. These are n-acylated alpha amino acids which have the L-configuration of the alpha-carbon atom. N-a-Acetyl-L-arginine serum levels (and other guanidino compounds) were elevated of all the hyperargininemic patients are higher than the normal range. N-a-Acetyl-L-arginine is a very strong basic compound (based on its pKa). Untreated hyperargininemic patients have the highest guanidino compound levels in cerebrospinal fluid. N-a-Acetyl-L-arginine is one of the guanidino compounds found elevated in the serum of an hemodialyzed renal insufficient (uremic) pediatric population. Outside of the human body, N-a-Acetyl-L-arginine has been detected, but not quantified in, apples and loquats. This could make N-a-acetyl-L-arginine a potential biomarker for the consumption of these foods. N-a-Acetyl-L-arginine, with regard to humans, has been found to be associated with several diseases such as uremia and colorectal cancer, N-a-acetyl-L-arginine has also been linked to the inborn metabolic disorder hyperargininemia. During a low-arginine diet, together with sodium benzoate therapy, there was a marked decrease in plasma N-alpha-acetylarginine. N-a-Acetyl-L-arginine increases in urine hyperargininemic patients. |
| Pathway: | Metabolism |
| Target: | Endogenous Metabolite |
| Receptor: | Human Endogenous Metabolite |
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