Western blot analysis of extracts of 293T cells, using BRCA2 antibody (A2435) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
BRCA2 Rabbit pAb
Catalog No:AB-A2435
Manufacturer:ABclonal
Synonyms:BRCA2;BRCC2;BROVCA2;FACD;FAD;FAD1;FANCD;FANCD1;GLM3;PNCA2;XRCC11
Applications:WB,IF
Reactivity:Human,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | BRCA2 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human BRCA2 (NP_000050.2). |
Gene ID: | 675 |
Swiss prot: | P51587 |
Molecular weight: | 384kDa |
Help & Support
Product
Guarantee and
Expert Support
Related products
Catalog No:AB-A0059
Manufacturer:ABclonal
Synonyms:BSCL3;CGL3;LCCNS;MSTP085;PPH3;VIP21;CAV1
Applications:IF
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Catalog No:AB-A0062
Manufacturer:ABclonal
Synonyms:CYP1A2;CP12;P3-450;P450(PA);CYPIA2
Applications:WB
Reactivity:Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Catalog No:AB-A0038
Manufacturer:ABclonal
Synonyms:BRAF;B-RAF1;B-raf;BRAF1;NS7;RAFB1
Applications:WB,IHC
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Catalog No:AB-A0040
Manufacturer:ABclonal
Synonyms:MET;AUTS9;DFNB97;HGFR;RCCP2;c-Met
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Catalog No:AB-A0027
Manufacturer:ABclonal
Synonyms:CANDF7;IMD31A;IMD31B;IMD31C;ISGF-3;STAT91;STAT1 alpha;STAT1
Applications:WB,IHC
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Catalog No:AB-A0003
Manufacturer:ABclonal
Synonyms:OSRC;PPP1R130;RB;p105-Rb;pRb;pp110;RB1;Rb
Applications:WB,IF
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €485,00