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Western blot analysis of extracts of various cell lines, using BMPR1B Rabbit pAb (A2005) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
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Immunohistochemistry of paraffin-embedded mouse kidney using BMPR1B Rabbit pAb (A2005) at dilution of 1:350 (40x lens).
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Immunohistochemistry of paraffin-embedded rat ovary using BMPR1B Rabbit pAb (A2005) at dilution of 1:350 (40x lens).
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Immunofluorescence analysis of L929 cells using BMPR1B antibody (A2005) at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunohistochemistry of paraffin-embedded mouse kidney using BMPR1B Rabbit pAb (A2005) at dilution of 1:350 (40x lens).
Immunohistochemistry of paraffin-embedded rat ovary using BMPR1B Rabbit pAb (A2005) at dilution of 1:350 (40x lens).
BMPR1B Rabbit pAb
Catalog No：AB-A2005
Manufacturer：ABclonal
Synonyms：ALK-6;ALK6;AMDD;BDA1D;BDA2;CDw293;BMPR1B
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | BMPR1B Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-126 of human BMPR1B (NP_001194.1). |
| Gene ID: | 658 |
| Swiss prot: | O00238 |
| Molecular weight: | 56kDa/60kDa |
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